New hope for seniors with hodgkin lymphoma: Chemo-Free combo shows promise

NCT ID NCT02758717

First seen Sep 30, 2025 · Last updated Apr 28, 2026 · Updated 30 times

Summary

This study tests a combination of two drugs, nivolumab and brentuximab vedotin, in people aged 60 and older (or younger people who cannot take standard chemotherapy) with untreated Hodgkin lymphoma. The goal is to see how well these drugs control the cancer by helping the immune system attack it. About 46 participants will receive the treatment for up to 8 cycles, and doctors will measure how many achieve a complete or partial metabolic response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Stanford Cancer Institute Palo Alto

    Palo Alto, California, 94304, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.