Experimental combo aims to revive immune attack on tough lymphoma

NCT ID NCT05162976

First seen Jun 07, 2026 · Last updated Jun 15, 2026 · Updated 2 times

Summary

This early-phase study tests whether adding an oral drug (CC-486) to the immunotherapy nivolumab can help people with Hodgkin lymphoma whose cancer did not respond to PD-1 therapy. CC-486 may make cancer cells more visible to the immune system, potentially restoring nivolumab's effectiveness. The trial involves 33 adults and focuses on safety and tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.