Which home breathing machine best prevents COPD Flare-Ups? major trial launches
NCT ID NCT07047092
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a non-invasive ventilator (NIV) or a CPAP machine is better at preventing severe COPD flare-ups and death in people who also have sleep apnea. About 386 adults who recently survived a life-threatening breathing crisis will use one of the two machines at home for a year. The goal is to see which device reduces hospital readmissions and improves breathing control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Non-invasive ventilation (NIV) or continuous positive airway pressure (CPAP) devices
- What this could lead to
- If this trial succeeds, it could show which breathing machine (NIV or CPAP) works best at home to prevent future severe COPD flare-ups and hospital stays in people who also have sleep apnea.
- What could go wrong
- This is a phase 3 trial, but it only compares two existing devices, not a new drug. The benefit may be modest, and results may not apply to all patients with COPD and sleep apnea.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Pitié-Salpêtrière - Sleep unit, R3S Departement
RECRUITINGParis, 75013, France
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