Could a simple mouth rinse lower blood pressure? early trial hints yes

NCT ID NCT05798481

First seen Dec 18, 2025 · Last updated May 25, 2026 · Updated 20 times

Summary

This early-phase study tested a new way to deliver nitric oxide—a molecule that relaxes blood vessels—by placing a mixture under the tongue. Fourteen healthy adults took part to see if this method safely lowers blood pressure. The goal is to find an alternative to current nitrate drugs that avoids building up tolerance over time.

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Contacts and locations

Locations

  • Anesthesiology and Perioperative Medicine

    Birmingham, Alabama, 35294, United States

Conditions

Explore the condition pages connected to this study.