New combo therapy trial offers hope for Tough-to-Treat breast cancer

NCT ID NCT03368729

Summary

This study is testing whether adding a pill called niraparib to the standard IV drug trastuzumab is safe and effective for people with advanced HER2-positive breast cancer that has spread. It's for patients whose cancer has grown despite previous HER2-targeted treatments. The main goals are to find the safest dose and see if the combination helps shrink tumors.

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Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Montefiore

    The Bronx, New York, 10461, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Washington-

    Seattle, Washington, 98109, United States

Conditions

Explore the condition pages connected to this study.