New drug cocktail shows promise in battling advanced head and neck cancer
NCT ID NCT05784012
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding two drugs, niraparib and dostarlimab, to standard radiation therapy can better control advanced head and neck cancer. About 34 adults with stage III or IV cancer will receive the drugs before, during, and after radiation. The goal is to see if this combination improves disease-free survival and overall control of the cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Complejo Hospitalario de Navarra
Pamplona, Navarre, 31008, Spain
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Hospital Clinic de Barcelona
Barcelona, Catalonia, 08036, Spain
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Hospital Clínico Universitario de Valencia
Valencia, Valencia, 46010, Spain
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Hospital Universitario 12 de Octubre
Madrid, Madrid, 28041, Spain
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Hospital Universitario Valle Hebron
Barcelona, Catalonia, 08035, Spain
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Institut Catalá d'Oncologia (ICO) BADALONA
Badalona, Catalonia, 08916, Spain
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Institut Catalá d'Oncologia (ICO) Hospitalet
L'Hospitalet de Llobregat, Catalonia, 08908, Spain