New hope for kids with rare Muscle-Weakening disease?
NCT ID NCT05265273
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called nipocalimab in children aged 2 to 18 with generalized myasthenia gravis, a condition that causes muscle weakness. The goal is to see if the drug safely lowers certain immune proteins (IgG) and improves daily activities. About 12 children will receive the drug alongside their current standard care.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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C.S. Mott Children's Hospital
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Chiba University Hospital
COMPLETEDChiba, 260 8677, Japan
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Children's Hospital Colorado
RECRUITINGAurora, Colorado, 80045, United States
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Childrens Hospital Los Angeles
RECRUITINGLos Angeles, California, 90027, United States
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Childrens Hospital Of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19106, United States
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Hyogo College of Medicine Hospital
RECRUITINGNishinomiya-Shi, 663-8501, Japan
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Leiden University Medical Center
RECRUITINGLeiden, 2333 ZA, Netherlands
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Lucile Packard Children's Hospital Stanford
RECRUITINGPalo Alto, California, 94304, United States
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Nagano Children's Hospital
RECRUITINGAzumino-shi, 399-8288, Japan
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Penn State Milton S Hershey Medical Ctr
RECRUITINGHershey, Pennsylvania, 17033, United States
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Phoenix Children's Hospital
RECRUITINGPhoenix, Arizona, 85016, United States
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Saitama Prefecture Children's Medical Center
RECRUITINGSaitama Shi, 330-8777, Japan
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Tokyo Women's Medical University Hospital
RECRUITINGShinjuku-ku, 162-8666, Japan
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UCSF Benioff Children's Hospital
RECRUITINGSan Francisco, California, 94158, United States
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University of Kansas Medical Center
COMPLETEDLawrence, Kansas, 66045, United States
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University of Miyazaki Hospital
RECRUITINGMiyazaki, 889-1692, Japan
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University of Pittsburgh Medical Center
TERMINATEDPittsburgh, Pennsylvania, 15224, United States
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University of South Florida Morsani Center for Advanced Healthcare
RECRUITINGTampa, Florida, 33613, United States
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Uniwersyteckie Centrum Kliniczne
RECRUITINGGdansk, 80 211, Poland