New hope for lung cancer patients whose treatment stopped working

NCT ID NCT03758287

First seen May 14, 2026 · Last updated May 16, 2026 · Updated 2 times

Summary

This study tested a combination of two drugs (ningetinib and gefitinib) in 108 people with advanced non-small cell lung cancer whose tumors had a specific gene change (EGFR mutation) but not another (T790M), and whose cancer had stopped responding to standard targeted therapy. The goal was to find the safest dose and see if the combination could shrink tumors or slow the disease. This is not a cure, but aims to control the cancer for a longer time.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

Conditions

Explore the condition pages connected to this study.