Blood pressure drug may curb alcohol cravings in heavy drinkers
NCT ID NCT07681869
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether nimodipine, a blood pressure medication, can reduce alcohol consumption and craving in adults with Alcohol Use Disorder who are heavy drinkers. Participants receive nimodipine or a placebo over 18 hours, then take part in a controlled drinking session where they can choose between alcohol or money. The trial measures how many drinks they consume, their craving levels, and the stimulating or sedating effects of alcohol.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nimodipine
What this could lead to
If it works, this could point toward a medication that helps heavy drinkers cut back on alcohol by reducing craving and the stimulating effects of drinking.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. The drug is given for just 18 hours, so any effects may be short-lived.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Ketamine for Depression & Alcohol Use Disorder T NCT06090422
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Yale University School of Medicine (Connecticut Mental Health Center)
New Haven, Connecticut, 06519, United States