Could a leukemia drug slow Alzheimer's? small study tests safety

NCT ID NCT02947893

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tested a low dose of nilotinib, a drug used for leukemia, in 37 people with mild to moderate Alzheimer's disease. The goal was to see if the drug is safe and can reach the brain to affect proteins linked to Alzheimer's, like tau and amyloid. Participants took the drug or a placebo daily for a period, and researchers monitored side effects and changes in spinal fluid and brain scans. The study was small and focused on safety, so it does not prove the drug works for Alzheimer's.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALZHEIMER'S DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Georgetown University Medical Center

    Washington D.C., District of Columbia, 20057, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.