Could a leukemia drug slow Alzheimer's? small study tests safety
NCT ID NCT02947893
First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times
Summary
This study tested a low dose of nilotinib, a drug used for leukemia, in 37 people with mild to moderate Alzheimer's disease. The goal was to see if the drug is safe and can reach the brain to affect proteins linked to Alzheimer's, like tau and amyloid. Participants took the drug or a placebo daily for a period, and researchers monitored side effects and changes in spinal fluid and brain scans. The study was small and focused on safety, so it does not prove the drug works for Alzheimer's.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Georgetown University Medical Center
Washington D.C., District of Columbia, 20057, United States
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