Glowing dye could help lung cancer patients keep more healthy lung tissue

NCT ID NCT02570815

Recruiting now Disease control Sponsor: St. Joseph's Healthcare Hamilton Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a dye called indocyanine green (ICG) can help surgeons see the exact boundary of a lung cancer tumor during robotic surgery. The dye makes the healthy lung glow, leaving the cancerous segment dark. The surgeon then removes only that dark segment, sparing more healthy tissue. The trial involves 250 adults with early-stage non-small cell lung cancer and aims to see if this technique is accurate and safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: indocyanine green (ICG) dye
What this could lead to: If successful, this technique could allow more patients with early lung cancer to have a smaller, lung-sparing surgery instead of removing an entire lobe.
What could go wrong: This is an early Phase 1 trial focused on feasibility, not yet on long-term outcomes. The dye may cause allergic reactions, and the approach may not work for all patients.

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Conditions

The condition(s) this trial relates to.

lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER

Contacts and locations

Locations

St. Joseph's Healthcare Hamilton
RECRUITING

Hamilton, Ontario, L8N 4A6, Canada

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