Brain scans reveal how fast nicotine breakdown affects cravings

NCT ID NCT03442413

First seen Feb 03, 2026 · Last updated May 13, 2026 · Updated 9 times

Summary

This study looks at how quickly smokers break down nicotine and how that affects brain receptors linked to addiction. Thirteen adult smokers will have PET brain scans after one night and two nights without smoking, with a nicotine injection during one scan. The goal is to understand why some people have a harder time quitting, which could lead to better treatments.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.