Vitamin B3 pill may supercharge brain energy, small study hints

NCT ID NCT07649161

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking high doses of nicotinamide riboside (a form of vitamin B3) for two weeks can improve brain energy metabolism in 50 healthy adults. Researchers will use special MRI scans and blood tests to measure changes in key brain chemicals. There is no direct health benefit for participants, but the results may help design future studies for brain disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nicotinamide riboside (Niagen), a form of vitamin B3

What this could lead to

If it works, this could provide a foundation for future studies testing NR as a treatment for brain disorders linked to energy problems.

What could go wrong

This is a small, early study in healthy people, not patients. It only lasts 2 weeks, so any effects may be temporary or not apply to disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dauten Family Center for Bipolar Treatment Innovation

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••