Heart attack drug may fix 'Hidden' vessel damage

NCT ID NCT06787430

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether the drug nicorandil can improve blood flow in the heart's tiny vessels after a heart attack. About 170 patients having emergency angioplasty will receive either nicorandil or a placebo directly into their heart artery. The goal is to see if nicorandil reduces microvascular dysfunction, a common problem that can lead to worse outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
nicorandil
What this could lead to
If it works, this could point toward a simple, cheap way to improve blood flow in the heart's tiny vessels after a heart attack, potentially reducing long-term damage.
What could go wrong
This is a relatively small, early-phase trial testing a short-term drug effect. The benefit may be small or not translate to better long-term outcomes, and the drug can cause low blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for STEMI - ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.