Heart attack drug may fix 'Hidden' vessel damage

NCT ID NCT06787430

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug nicorandil can improve blood flow in the heart's tiny vessels after a heart attack. About 170 patients having emergency angioplasty will receive either nicorandil or a placebo directly into their heart artery. The goal is to see if nicorandil reduces microvascular dysfunction, a common problem that can lead to worse outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nicorandil

What this could lead to

If it works, this could point toward a simple, cheap way to improve blood flow in the heart's tiny vessels after a heart attack, potentially reducing long-term damage.

What could go wrong

This is a relatively small, early-phase trial testing a short-term drug effect. The benefit may be small or not translate to better long-term outcomes, and the drug can cause low blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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