New drug aims to stop cancer wasting in colorectal patients
NCT ID NCT07033026
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a drug called NGM120 in people with colorectal cancer who are losing weight due to cancer cachexia. The goal is to see if NGM120 can help patients gain or maintain weight and improve their quality of life. About 136 participants will receive either NGM120 or a placebo every 4 or 8 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
NGM120
What this could lead to
If it works, this could lead to a treatment that helps colorectal cancer patients with cachexia maintain or gain weight and feel better.
What could go wrong
This is an early Phase 2 trial with only 136 participants, so results may not apply to everyone. The drug may not improve weight or could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NGM Clinical Study Site
RECRUITINGLos Angeles, California, 90033, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGLos Angeles, California, 90095, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGSanta Rosa, California, 95403, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGMargate, Florida, 33063, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGBaltimore, Maryland, 21201, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGNew York, New York, 10065, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGToledo, Ohio, 43608, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGYoungstown, Ohio, 44504, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGDallas, Texas, 75390, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
WITHDRAWNKingwood, Texas, 77339, United States
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NGM Clinical Study Site
RECRUITINGLaredo, Texas, 78041, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGRichmond, Virginia, 23114, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGAppleton, Wisconsin, 54915, United States
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGTbilisi, 159, Georgia
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NGM Clinical Study Site
RECRUITINGTbilisi, 159, Georgia
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NGM Clinical Study Site
RECRUITINGTbilisi, 159, Georgia
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NGM Clinical Study Site
RECRUITINGTbilisi, 159, Georgia
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGTbilisi, 186, Georgia
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGGoyang, 10326, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGGoyang, 1048, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGIncheon, 21565, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGSeoul, 2841, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGSeoul, 3080, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGSeoul, 6351, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGSuwon, 16247, South Korea
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGTaichung, 407216, Taiwan
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGTaipei, 100225, Taiwan
Contact Email: •••••@•••••
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NGM Clinical Study Site
RECRUITINGTaoyuan, 333423, Taiwan
Contact Email: •••••@•••••