New tests aim to spot bone marrow graft failure early

NCT ID NCT03541889

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing two new ways to check if donated bone marrow cells are growing well after a transplant. Researchers will use a special PET scan (FLT imaging) and blood tests (TK1 levels) in about 56 people who are at high risk for graft failure. The goal is to find better tools to detect problems early, so doctors can act quickly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
FLT imaging and TK1 blood measurements
What this could lead to
If successful, these tests could help doctors quickly tell if a bone marrow transplant is working, allowing earlier treatment for graft failure.
What could go wrong
This is a small, early-phase pilot study (56 people) testing new methods, so results may not apply broadly or lead to a proven test.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • University Hospital of Cleveland UH Seidman Cancer Center

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of Oklahoma Health Sciences Center, Stephenson Cancer Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

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