New polio vaccine combo tested in infants: could speed up eradication

NCT ID NCT06895486

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: PATH Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving two new oral polio vaccines (types 1 and 2) together is safe and works as well as giving them separately in healthy 16-week-old infants. About 675 babies in Panama will receive either the combo or single vaccines. The goal is to see if the combo approach can simplify vaccination and help wipe out polio for good.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Novel Oral Polio Vaccine Type 1 and Type 2 (nOPV1 and nOPV2)
What this could lead to: If successful, this could lead to a more efficient way to protect infants against polio by giving two vaccine types at once, helping to eradicate polio globally.
What could go wrong: This is a phase 2 trial with 675 infants, so it's still early. The vaccines may not work as well when given together, or could cause more side effects. Results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

poliomyelitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLIOMYELITIS

Contacts and locations

Locations

Cevaxin - 24 de Diciembre
RECRUITING

Panama City, Panama
Cevaxin - Ave. México
RECRUITING

Panama City, Panama
Cevaxin - Chorrera
RECRUITING

Panama City, Panama

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