New vaccine V118C aims to shield kids from pneumococcal disease

NCT ID NCT07300267

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new vaccine called V118C to prevent pneumococcal disease, which can cause serious lung and other infections. About 210 toddlers and infants will receive either V118C or an existing vaccine to compare safety and immune response. The study is currently recruiting participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: V118C vaccine
What this could lead to: If successful, this could lead to a new vaccine option to protect children against pneumococcal infections like pneumonia and meningitis.
What could go wrong: This is an early phase 1 trial focused on safety, so it's too soon to know if the vaccine works. Side effects like injection-site reactions or fever are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PNEUMOCOCCAL INFECTION

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Acevedo Clinical Research Associates ( Site 1029)
RECRUITING

Miami, Florida, 33142, United States
Child Health Care Associates ( Site 1035)
RECRUITING

East Syracuse, New York, 13057, United States
Cotton O'Neil Research Center ( Site 1039)
RECRUITING

Topeka, Kansas, 66604, United States
Epic Medical Research - Carrollton ( Site 1038)
RECRUITING

Carrollton, Texas, 75006, United States
Epic Medical Research- Garland ( Site 1017)
RECRUITING

Garland, Texas, 75043, United States
Madera Family Medical Group ( Site 1004)
RECRUITING

Madera, California, 93637, United States
Pediatric Research of Charlottesville, LLC ( Site 1012)
RECRUITING

Charlottesville, Virginia, 22902, United States
Saint Louis University Center for Vaccine Development ( Site 1031)
RECRUITING

St Louis, Missouri, 63104, United States
The Pediatric Center ( Site 1025)
RECRUITING

Columbia, Maryland, 21045, United States
Tribe Clinical Research - Spartanburg ( Site 1001)
RECRUITING

Spartanburg, South Carolina, 29301, United States
Tribe Clinical Research, LLC-Pediatrics ( Site 1008)
RECRUITING

Greenville, South Carolina, 29607, United States
University of Louisville, Norton Children's Research Institute ( Site 1005)
RECRUITING

Louisville, Kentucky, 40202, United States
University of South Florida-Department of Pediatrics ( Site 1002)
RECRUITING

Tampa, Florida, 33606, United States
University of Texas Medical Branch ( Site 1020)
RECRUITING

League City, Texas, 77573, United States

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