Mouth rinse could replace painful lung tests for pneumonia diagnosis

NCT ID NCT00342589

First seen Jan 10, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This study tested whether a simple saltwater mouth rinse can detect pneumocystis, a lung infection that can be life-threatening for people with weak immune systems (like those with HIV, cancer, or organ transplants). Current diagnosis requires coughing up lung fluid or a tube inserted into the lungs, which can be uncomfortable and time-consuming. Researchers collected mouth rinse and blood samples from over 1,000 participants to see if new lab techniques could make diagnosis easier and less invasive.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.