Four-Drug attack on blood cancer shows promise in early trial

NCT ID NCT02969837

Summary

This completed Phase 2 trial tested a combination of four medications (elotuzumab, carfilzomib, lenalidomide, and dexamethasone) as the first treatment for 46 adults newly diagnosed with multiple myeloma, a cancer of plasma cells. The main goal was to see how many patients achieved a very deep response, meaning no detectable cancer cells could be found using sensitive tests after eight cycles of treatment. Researchers also tracked safety, how long patients lived without the cancer worsening, and overall survival.

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Contacts and locations

Locations

  • NorthShore University Health System

    Evanston, Illinois, 60201, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

Conditions

Explore the condition pages connected to this study.