Four-Drug attack on blood cancer shows promise in early trial

NCT ID NCT03290950

Summary

This study is testing whether combining four medications—daratumumab, carfilzomib, lenalidomide, and dexamethasone—is safe and effective for people newly diagnosed with multiple myeloma, a cancer of plasma cells in the bone marrow. The main goal is to see if this combination can make the cancer undetectable by sensitive tests, a state called 'minimal residual disease negativity.' The trial is for adults who have not yet received treatment for their myeloma, aside from possibly one prior cycle of therapy.

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Contacts and locations

Locations

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.