New MRI technique could spot brain tumors without a biopsy
NCT ID NCT04772456
First seen Oct 31, 2025 · Last updated Jun 21, 2026 · Updated 37 times
Summary
This early-phase study tests a new MRI technique that uses a special substance called hyperpolarized pyruvate to make brain tumors easier to see. The goal is to see if this method is safe and more accurate than standard MRI for diagnosing gliomas. Up to 5 adults with suspected or known brain tumors will take part at the University of Maryland.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Rosy Njonkou Tchoquessi
RECRUITINGBaltimore, Maryland, 21201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyperpolarized 13C-Pyruvate injection
What this could lead to
If successful, this could lead to a more accurate, non-invasive way to diagnose brain tumors using MRI, potentially reducing the need for biopsies.
What could go wrong
This is a very early, small study with only 5 participants, so results may not apply to everyone. The technique is still experimental and may not prove more useful than current methods.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.