New cancer drug targets KRAS mutations in first human trial

NCT ID NCT07300150

Summary

This is the first human study of an experimental drug called PT0511 for people with advanced solid tumors that have specific KRAS genetic changes. The main goals are to find safe doses and see how the body processes the drug, both alone and combined with another cancer medication for colorectal cancer. Researchers will enroll about 195 adults who have tried 1-4 other treatments to test safety and look for early signs of effectiveness.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber/Massachusetts General Hospital, Inc

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Email: •••••@•••••

  • New Experimental Therapeutics of San Antonio LLC

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Email: •••••@•••••

  • START - South Texas Accelerated Research Therapeutics, LLC

    NOT_YET_RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Email: •••••@•••••

  • START Mountain Region

    NOT_YET_RECRUITING

    West Valley City, Utah, 84119, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.