New HOLD-B score could revolutionize emergency bleeding risk assessment

NCT ID NCT07458178

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 312 adults with upper gastrointestinal bleeding to create a new risk score called HOLD-B. The score uses four simple factors (hemoglobin, lactate, diastolic blood pressure, and blood urea nitrogen) to predict which patients are at high risk for needing a transfusion, intensive care, or other interventions. The goal is to give emergency doctors a quick, easy tool to make better treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this new scoring system could help doctors quickly identify high-risk patients with upper gastrointestinal bleeding, leading to faster and more appropriate care.
What could go wrong
This is a small, single-center retrospective study. The new score needs to be tested in larger, more diverse groups before it can be widely used.

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Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Izmir Katip Çelebi University Faculty of Medicine

    Izmir, Turkey (Türkiye)

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