New hope for rare sarcomas: Triple-Drug combo targets tumors

NCT ID NCT05253131

First seen Jan 08, 2026 · Last updated Apr 29, 2026 · Updated 14 times

Summary

This study tests a combination of three drugs (selumetinib, ZEN-3694, and durvalumab) in adults with sarcomas, including a rare nerve tumor called MPNST. The goal is to see if the combination is safe and can shrink or stabilize tumors. The study is for people whose cancer has not responded to other treatments or cannot be removed by surgery.

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Contacts and locations

Locations

  • The University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.