Scientists attack 'Chemo-Resistant' breast cancer with new drug cocktail

NCT ID NCT05660083

Summary

This study is testing a new three-drug combination for people with a rare and aggressive type of breast cancer called metaplastic breast cancer (MpBC), which has stopped responding to standard treatments. The goal is to see if adding two new drugs (alpelisib and L-NMMA) to a standard chemotherapy (nab-paclitaxel) can help control the cancer better. The trial will enroll about 36 adults with advanced, HER2-negative MpBC to test the safety and effectiveness of this approach.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Houston Methodist Neal Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

  • National Institute of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.