New combo aims to deepen remission in early CML

NCT ID NCT05007873

First seen Jan 10, 2026 · Last updated Jun 13, 2026 · Updated 29 times

Summary

This study tests whether adding ASTX727 to the standard drug dasatinib can better control chronic myeloid leukemia (CML) in newly diagnosed patients. About 70 adults with a specific genetic marker (Philadelphia chromosome) will receive both pills. The goal is to see if the combination leads to deeper, longer-lasting responses without increasing side effects.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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