New pill aims to crush stubborn cholesterol in High-Risk patients

NCT ID NCT06005597

Summary

This study tested whether a new combination pill containing two drugs (obicetrapib and ezetimibe) could lower 'bad' cholesterol (LDL-C) more effectively than a placebo or either drug alone. It involved 407 adults with a genetic cholesterol disorder (HeFH) or established heart disease who were already on the strongest cholesterol medications they could tolerate. The goal was to see if adding this new pill provided better cholesterol control to help prevent future heart attacks and strokes.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alpine Research Organization, Inc.

    Clinton, Utah, 84015, United States

  • Amarillo Heart Clinical Research Institute, Inc

    Amarillo, Texas, 79124, United States

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Capital Area Research

    Camp Hill, Pennsylvania, 17074, United States

  • Cardiovascular Research of Knoxville

    Powell, Tennessee, 37849, United States

  • Cardiovascular Research of Northwest Indiana, LLC

    Munster, Indiana, 46321, United States

  • Cary Research Group, LLC

    Cary, North Carolina, 27518, United States

  • Center for Advanced Research and Education

    Gainesville, Georgia, 30501, United States

  • CentraCare Heart & Vascular Center

    Saint Cloud, Minnesota, 56303, United States

  • Centricity Research - Columbus

    Columbus, Georgia, 31904, United States

  • Chattanooga Research & Medicine, PLLC

    Chattanooga, Tennessee, 37404, United States

  • DM Clinical Research

    Houston, Texas, 77375, United States

  • Diabetes and Thyroid Center of Fort Worth

    Fort Worth, Texas, 76132, United States

  • East Valley Diabetes & Endocrinology

    Gilbert, Arizona, 85297, United States

  • Evanston Premier Healthcare Research LLC

    Skokie, Illinois, 60077, United States

  • Grace Research, LLC - Bossier City, LA

    Bossier City, Louisiana, 71111, United States

  • Hampton Roads Center for Clinical Research

    Suffolk, Virginia, 23435, United States

  • Horizon Research Group of Opelousas

    Eunice, Louisiana, 70535, United States

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida, 32216, United States

  • Juno Research, LLC - Medical Center Office

    Houston, Texas, 77054, United States

  • Lucas Research, Inc

    Morehead City, North Carolina, 28557, United States

  • Maryland Cardiovascular Specialists

    Baltimore, Maryland, 21229, United States

  • McClaren Bay Heart and Vascular

    Bay City, Michigan, 49770, United States

  • Metabolic and Atherosclerosis Research Center

    Cincinnati, Ohio, 45227, United States

  • Monument Health Clinical Research, a department of Monument Health Rapid City Hospital, Inc

    Rapid City, South Dakota, 57701, United States

  • NSC Research

    Johns Creek, Georgia, 30024, United States

  • North Georgia Clinical Research

    Woodstock, Georgia, 30189, United States

  • North Mississippi Medical Center

    Tupelo, Mississippi, 38801, United States

  • Northern Pines Health Center

    Buckley, Michigan, 49620, United States

  • Northwest Houston Heart Center

    Tomball, Texas, 77375, United States

  • Novant Health Clinical Research, LLC

    Charlotte, North Carolina, 27701, United States

  • Novant Health Heart and Vascular Institute

    Charlotte, North Carolina, 28204, United States

  • Oakland Medical Research Center

    Troy, Michigan, 48085, United States

  • PharmaTex Research, LLC

    Amarillo, Texas, 79109, United States

  • Progressive Medical Research

    Port Orange, Florida, 32127, United States

  • South Texas Clinical Research

    Corpus Christi, Texas, 78404, United States

  • Sparrow Clinical Research Institute

    Lansing, Michigan, 48912, United States

  • Spectrum Medical, Inc.

    Danville, Virginia, 24541, United States

  • St. Louis Heart and Vascular Cardiology

    St Louis, Missouri, 63136, United States

  • Summit Research Group, LLC

    Stow, Ohio, 44240, United States

  • TidalHealth Peninsula Regional, Inc.

    Salisbury, Maryland, 21804, United States

  • Triad Internal Medicine

    Asheboro, North Carolina, 27203, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63136, United States

  • Wellness Clinical Research Associates

    McKinney, Texas, 75069, United States

  • Wilmington Health Associates

    Wilmington, North Carolina, 28412, United States

Conditions

Explore the condition pages connected to this study.