Major trial tests new hope for millions battling stubborn high cholesterol

NCT ID NCT05142722

Summary

This large, completed Phase 3 trial tested whether a new drug called obicetrapib could help people with high cholesterol and heart disease who weren't getting enough benefit from their current medications. Over 2,500 participants took either the new pill or a placebo (a dummy pill) for a year, in addition to their standard treatments. The main goal was to see if obicetrapib could safely lower 'bad' cholesterol (LDL-C) more effectively.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • 4 Wojskowy Szpital Kliniczny z Poliklinika Samodzielny Publiczny ZOZ we Wroclawiu

    Wroclaw, 50-981, Poland

  • AB Clinical Trials

    Las Vegas, Nevada, 89119, United States

  • Aarhus University Hospital

    Aarhus, 8200, Denmark

  • Acad. G. Chapidze Emergency Cardiology Center LTD

    Tbilisi, 0159, Georgia

  • Academic Medical Center - Department of Vascular Medicine

    Amsterdam, 1105 AZ, Netherlands

  • Adapti LTD

    Tbilisi, 0186, Georgia

  • Advanced Research Institute Inc

    New Port Richey, Florida, 34653, United States

  • Affiliated Hospital of Chifeng University

    Chifeng, 24050, China

  • Aka-Med Centrum Spólka Z Ograniczona Odpowiedzialnoscia

    Ruda Śląska, 41-710, Poland

  • Albert Schweitzer Ziekenhuis - Location Dordrecht

    Zwijndrecht, 3331 LZ, Netherlands

  • Alta Pharmaceutical Research Center

    Peachtree Corners, Georgia, 30092, United States

  • Amager Hospital

    Copenhagen S, 2300, Denmark

  • Amarillo Heart Clinical Research Institute, Inc

    Amarillo, Texas, 79106, United States

  • American Institute of Research

    Beverly Hills, California, 90211, United States

  • Apex Mobile Clinical Research

    Bellaire, Texas, 77401, United States

  • Arcturus Healthcare, Troy Internal Medicine Research Division

    Troy, Michigan, 48098, United States

  • Biofortis, Inc

    Addison, Illinois, 60101, United States

  • Bokhua Memorial Cardiovascular Center LTD

    Tbilisi, 0159, Georgia

  • Bravis ziekenhuis - Locatie Roosendaal

    Roosendaal, 4708 AE, Netherlands

  • CCR Czech a.s.

    Pardubice, 530 02, Czechia

  • CCR Ostrava s.r.o.

    Ostrava, 702 00, Czechia

  • CENTRUM MEDYCZNE INTERCOR Sp. z o.o.

    Bydgoszcz, 85-605, Poland

  • Cambridge Medical Trials

    Alexandria, Louisiana, 71301, United States

  • Cangzhou Central Hospital

    Cangzhou, 61017, China

  • Canisius-Wilhelmina Ziekenhuis (CWZ)

    Nijmegen, 6532 SZ, Netherlands

  • Cardiovascular Research of Knoxville, LLC

    Powell, Tennessee, 37849, United States

  • Central Alabama Research

    Birmingham, Alabama, 35209, United States

  • Centricity Research

    Columbus, Georgia, 31904, United States

  • Centrum Medyczne Kermed - Renata Bijata-Bronisz I Ewa Kowalinska Spólka Jawna

    Bydgoszcz, 85-231, Poland

  • Centrum pro zdravi - kardiologie s.r.o.

    Brno, 603 00, Czechia

  • Cevni ambulance - MATMED s.r.o.

    Hodonín, 695 01, Czechia

  • Chear Center LLC

    The Bronx, New York, 10455, United States

  • Chiba University Hospital

    Chiba, 260-8677, Japan

  • Chifeng Municipal Hospital

    Chifeng, 24099, China

  • China-Japan Union Hospital Of Jilin University

    Changchun, 130033, China

  • ClinCloud LLC

    Maitland, Florida, 32751, United States

  • Clinical Best Solutions - Lublin

    Lublin, 20-078, Poland

  • Clinical Best Solutions Sp. z.o.o Spolka Komandytowa

    Warsaw, 00-710, Poland

  • Clinical Research Institute of Arizona, LLC

    Sun City West, Arizona, 85375, United States

  • Columbus Clinical Services, LLC

    Miami, Florida, 33125, United States

  • Cotton-O'Neil Clinical Research Center

    Topeka, Kansas, 66606, United States

  • Daqing People's Hospital

    Daqing, 163711, China

  • Diabetes and Endocrinology Consultants, P.C.

    Morehead City, North Carolina, 28557, United States

  • East Coast Institute for Research

    Saint Augustine, Florida, 32086, United States

  • East Coast Institute for Research - Canton

    Canton, Georgia, 30114, United States

  • East Coast Institute for Research, LLC

    Jacksonville, Florida, 32204, United States

  • East Coast Institute for Research, LLC

    Macon, Georgia, 31210, United States

  • East Coast Institute for Research, LLC - Jacksonville University Blvd

    Jacksonville, Florida, 32216, United States

  • East Coast Institute for Research- Lake City

    Lake City, Florida, 32055, United States

  • Eclipse Clinical Research

    Tucson, Arizona, 85745, United States

  • Evanston Premier Healthcare Research LLC

    Skokie, Illinois, 60077, United States

  • Excel Medical Clinical Trials

    Boca Raton, Florida, 33434, United States

  • Foshan First People's Hospital

    Foshan, 528010, China

  • FutureMeds Lodz

    Lodz, 91-363, Poland

  • FutureMeds Sp. z o.o

    Wroclaw, 50-088, Poland

  • FutureMeds Targowek

    Warsaw, 03-291, Poland

  • FutureMeds Warszawa Centrum

    Warsaw, 00-215, Poland

  • Futuremeds Olsztyn

    Olsztyn, 10-010, Poland

  • Gelre Ziekenhuizen - Locatie Zutphen

    Zutphen, 7207 AE, Netherlands

  • Georgian-Ducht Hospital LTD

    Tbilisi, 0172, Georgia

  • Godstrup Regional Hospital (Gødstrup)

    Herning, 7400, Denmark

  • Grace Research, LLC

    Bossier City, Louisiana, 71111, United States

  • Grace Research, LLC

    Shreveport, Louisiana, 71105, United States

  • Guangdong Provincial People's Hospital

    Guangzhou, 510080, China

  • Hampton Roads Center for Clinical Research

    Suffolk, Virginia, 23434, United States

  • Health LTD

    Batumi, 6004, Georgia

  • Hebei Petro China Central Hospital

    Langfang, 65099, China

  • Heilongjiang Provincial Hospital

    Harbin, 150036, China

  • Hiroshima Prefectural Hospital

    Hiroshima, 734-8530, Japan

  • Hiroshima University Hospital

    Hiroshima, 734-8551, Japan

  • Hornicka nemocnice s poliklinikou Bilina s.r.o.

    Bílina, 418 01, Czechia

  • Huabei Petroleum Administration Bureau General Hospital

    Renqiu, 62550, China

  • Hyogo Prefectural Harima-Himeji General Medical Center

    Hyōgo, 670-8560, Japan

  • IJsselland ziekenhuis

    Capelle aan den IJssel, 2906 ZC, Netherlands

  • Ikazia Ziekenhuis

    Rotterdam, 3083 AN, Netherlands

  • Indywidualna Specjalistyczna Praktyka Lekarska Wlodzimierz Kus

    Lodz, 94-255, Poland

  • Indywidualna Specjalistyczna Praktyka Lekarska w Dziedzinie Kardiologii, lek. med. Krzysztof Cymerman

    Gdynia, 81-157, Poland

  • Inquest Clinical Research

    Baytown, Texas, 77521, United States

  • Inspira Medical Centers dba Internal Medicine Associates, P.A.

    Bridgeton, New Jersey, 08302, United States

  • Instytut Centrum Zdrowia Matki Polki

    Lodz, 93-338, Poland

  • Ishikawa Prefectural Central Hospital

    Ishikawa, 920-8530, Japan

  • JSC Curatio

    Tbilisi, 0114, Georgia

  • Japan Community Health Care Organization Kyushu Hospital

    Fukuoka, 806-8501, Japan

  • Javara Inc.

    Conroe, Texas, 77384, United States

  • Jeroen Bosch Ziekenhuis

    's-Hertogenbosch, 5223 GZ, Netherlands

  • Jinan Central Hospital

    Jinan, 250013, China

  • KARDIOLOGIE - LIBEREC s.r.o.

    Liberec, 46014, Czechia

  • KO - MED Centra Kliniczne Lublin II

    Lublin, 20-362, Poland

  • Kardiologicka ambulance Brno s.r.o.

    Brno, 612 00, Czechia

  • Kardiologie COR s.r.o.

    Prague, 106 00, Czechia

  • Kendall South Medical Center, Inc.

    Miami, Florida, 33185, United States

  • Kokura Memorial Hospital

    Kitakyushu, 802-8555, Japan

  • Komatsu Municipal Hospital

    Ishikawa, 923-8560, Japan

  • Krakowskie Centrum Medyczne Sp. z o.o.

    Krakow, 31-501, Poland

  • Laurentius Hospital Roermond

    Roermond, 6043 CV, Netherlands

  • Lillestol Research, LLC

    Fargo, North Dakota, 58104, United States

  • Lishui Central Hospital

    Lishui, 323020, China

  • Louisville Metabolic and Atherosclerosis Research Center (L-MARC)

    Louisville, Kentucky, 40213, United States

  • Luoyang Third People's Hospital

    Luoyang, 471002, China

  • MUDr. Tomas Edelsberger - diabetologicka ambulance

    Krnov, 794 01, Czechia

  • Manassas Clinical Research Center

    Manassas, Virginia, 20110, United States

  • Martini Ziekenhuis

    Groningen, 9728 NT, Netherlands

  • Medi Club Georgia LLC

    Tbilisi, 0160, Georgia

  • Medicus Services SRO

    Brandýs nad Labem, 250 01, Czechia

  • Mid Hudson Medical Research

    New Windsor, New York, 12553, United States

  • Midwest Institute for Clinical Research

    Indianapolis, Indiana, 46260, United States

  • Monument Health Clinical Research

    Rapid City, South Dakota, 57701, United States

  • NZOZ Twoje Zdrowie EL Sp. z o.o.

    Elblag, 82-300, Poland

  • National Cerebral and Cardiovascular Center Research Institute

    Osaka, 565-8565, Japan

  • New Generation of Medical Research

    Hialeah, Florida, 33016, United States

  • New Tokyo Heart Clinic

    Chiba, 271-0077, Japan

  • Niigata University Medical & Dental Hospital

    Niigata, 951-8510, Japan

  • Noordwest Ziekenhuisgroep

    Alkmaar, 1815 JD, Netherlands

  • Northern Light Cardiology

    Bangor, Maine, 04401, United States

  • Northwest Houston Clinical Research

    Tomball, Texas, 77375, United States

  • Nowe Zdrowie-Ck Kieltucki i Wspolnicy Spolka Jawna

    Staszów, 28-200, Poland

  • Oakland Medical Research

    Troy, Michigan, 48085, United States

  • Onze Lieve Vrouwe Gasthuis

    Amsterdam, 1091 AC, Netherlands

  • Orange County Research Center

    Tustin, California, 92780, United States

  • Osaka Medical and Pharmaceutical University Hospital

    Osaka, 569-8686, Japan

  • Ostrowieckie Centrum Medyczne spólka cywilna Anna Olech-Cudzik

    Ostrowiec Świętokrzyski, 27-400, Poland

  • Panjin Liaoyou Gem Flower Hospital

    Panjin, 124010, China

  • Peking University First Hospital

    Beijing, 100034, China

  • Pinnacle Research Group

    Anniston, Alabama, 36207, United States

  • Pioneer Clinical Studies

    Ft. Pierce, Florida, 34950, United States

  • PreventaMed s.r.o.

    Olomouc, 779 00, Czechia

  • Prime Revival Research Institute, LLC

    Coppell, Texas, 75019, United States

  • Privia Medical Group, LLC

    Silver Spring, Maryland, 20901, United States

  • Progressive Medical Research

    Port Orange, Florida, 32127, United States

  • Prywatny Gabinet Lekarski Jacek Gessek

    Torun, 87-100, Poland

  • Public Central Hospital of Matto lshikawa

    Ishikawa, 924-8588, Japan

  • Reinier de Graaf Gasthuis

    Delft, 2625 AD, Netherlands

  • Research Integrity, LLC

    Owensboro, Kentucky, 42303, United States

  • Sakurabashi Watanabe Hospital

    Osaka, 530-0001, Japan

  • Showa University Northern Yokohama Hospital

    Kanagawa, 224-8503, Japan

  • Silmedic Sp. z o.o.

    Katowice, 40-282, Poland

  • Slingeland Ziekenhuis

    Doetinchem, 7009 BL, Netherlands

  • SouthCoast Health

    Savannah, Georgia, 31406, United States

  • Southern Clinical Research, LLC

    Zachary, Louisiana, 70791, United States

  • St. Jansdal Ziekenhuis

    Harderwijk, 3844 DG, Netherlands

  • Summit Research Group, LLC

    Stow, Ohio, 44224, United States

  • Sydvestjysk Hospital

    Esbjerg, 6700, Denmark

  • Syed Research Consultants, LLC

    Sheffield, Alabama, 35660, United States

  • Synexus Clinical Research US, Inc.

    Vista, California, 92083, United States

  • Synexus Clinical Research US, Inc.

    The Villages, Florida, 32162, United States

  • Synexus Clinical Research US, Inc.

    Atlanta, Georgia, 30328, United States

  • Synexus Clinical Research US, Inc.

    Evansville, Indiana, 47714, United States

  • Synexus Clinical Research US, Inc.

    New York, New York, 10017, United States

  • Synexus Clinical Research US, Inc.

    Salt Lake City, Utah, 84106, United States

  • Synexus Clinical Research US, Inc. / Orange Grove Family Practice

    Tucson, Arizona, 85741, United States

  • Synexus Clinical Research US, Inc. / Simon Williamson Clinic, PC

    Birmingham, Alabama, 35211, United States

  • Tandem Clinical Research

    Marrero, Louisiana, 70072, United States

  • Tandem Clinical Research GI - Metairie

    Metairie, Louisiana, 70006, United States

  • Tandem Clinical Research GI, LLC

    New York, New York, 10033, United States

  • Tergooiziekenhuizen Blaricum

    Blaricum, 1261 AN, Netherlands

  • The Center for Clinical Trials, Inc

    Saraland, Alabama, 36571, United States

  • The First Affiliated Hospital Of University Of South China

    Hunan, 421001, China

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, 233017, China

  • The First Medical Center LTD

    Tbilisi, 0180, Georgia

  • The First People's Hospital of Changde City

    Changde, 415003, China

  • The First affiliated Hospital of Nanyang Medical College

    Nanyang, 473024, China

  • The Sakakibara Heart Institute of Okayama

    Okayama, 700-0804, Japan

  • The Second People's Hospital of Changzhou

    Changzhou, 213164, China

  • The Third Affiliated Hospital of Guangzhou Medical university

    Guangzhou, 510150, China

  • The Third Affiliatied Hospital of Xinxiang Medical University

    Xinxiang, 453000, China

  • Thyroid, Endocrinology & Diabetes, PA

    Dallas, Texas, 75208, United States

  • Tianjin Fourth Central Hospital

    Tianjin, 300143, China

  • Tianjin People's Hospital

    Tianjin, 300121, China

  • Tokyo Saiseikai Central Hospital

    Tokyo, 108-0073, Japan

  • Universal Research Group, LLC

    Tacoma, Washington, 98405, United States

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

  • Viborg Regional Hospital

    Viborg, 8800, Denmark

  • VieCuri Medisch Centrum

    Venlo, 5912 BL, Netherlands

  • Vitamedi LTD

    Tbilisi, 0159, Georgia

  • Wenzhou People's Hospital

    Wenzhou, 325099, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China

  • Xi'an Gaoxin Hospital

    Xi'an, 710075, China

  • Xianyang Hospital of Yan 'an University

    Xianyang, 712099, China

  • Zaozhuang Municipal Hospital

    Zaozhuang, 277102, China

  • Ziekenhuis Deventer

    Deventer, 7416 SE, Netherlands

  • Ziekenhuis Rijnstate

    Arnhem, 6815 AD, Netherlands

Conditions

Explore the condition pages connected to this study.