New 'Smart Bomb' drug targets tough cancers in major trial

NCT ID NCT06131840

Summary

This early-stage trial is testing the safety and dosing of an experimental drug called PF-08046050 in adults with advanced solid tumors that have returned or stopped responding to standard treatments. The drug is designed to attach to cancer cells and deliver a toxic payload directly to them. The study will enroll over 900 participants with various cancers, including colorectal, lung, stomach, and pancreatic cancers, to find the right dose and see if the drug helps control the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ApoEx NKS

    RECRUITING

    Stockholm, 17176, Sweden

  • Ascires CETIR

    RECRUITING

    Esplugues de Llobregat, 08950, Spain

  • Ascires Cetir

    RECRUITING

    Barcelona, 08029, Spain

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • City of Hope (City of Hope National Medical Center, City of Hope Medical Center)

    RECRUITING

    Duarte, California, 91010, United States

  • Diagnostic Centre

    RECRUITING

    London, Others, WlG 7AF, United Kingdom

  • Edinburgh Cancer Centre, Western General Hospital

    RECRUITING

    Edinburgh, Scotland, EH4 2XU, United Kingdom

  • Florida Cancer Specialists

    RECRUITING

    Orlando, Florida, 32827, United States

  • Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

  • Hospital Universitario HM Sanchinarro-CIOCC-START Madrid

    RECRUITING

    Madrid, 28050, Spain

  • IP Address: City of Hope Investigational Drug Services(IDS)

    RECRUITING

    Duarte, California, 91010, United States

  • Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet)

    RECRUITING

    L'Hospitalet de Llobregat, Catalunya [cataluña], 08908, Spain

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, Paris, 94805, France

  • Karolinska University Hospital

    RECRUITING

    Solna, 171 64, Sweden

  • Lothian Health Board

    RECRUITING

    Edinburgh, EH3 9DN, United Kingdom

  • Mayo Clinic

    RECRUITING

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Cancer Center

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Hospital

    RECRUITING

    Phoenix, Arizona, 85054, United States

  • McGill University Health Centre

    RECRUITING

    Montreal, Quebec, H4A 3J1, Canada

  • Netherlands Cancer Institute

    RECRUITING

    Amsterdam, 1066CX, Netherlands

  • Radiology

    RECRUITING

    London, W1G 8PP, United Kingdom

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • START Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    RECRUITING

    Salt Lake City, Utah, 84119, United States

  • Sarah Cannon Research Institute - Pharmacy

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute UK

    RECRUITING

    London, W1G 6AD, United Kingdom

  • Sarah Cannon Research Institute at Florida Cancer Specialists

    RECRUITING

    Orlando, Florida, 32827, United States

  • Servicio de Farmacia ICO - Planta 0

    RECRUITING

    L'Hospitalet de Llobregat, 08908, Spain

  • Sidney Kimmel Comprehensive Cancer at Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • South Texas Accelerated Research Therapeutics Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

  • South Texas Accelerated Research Therapeutics, LLC

    RECRUITING

    San Antonio, Texas, 78229, United States

  • The Harley Street Clinic

    RECRUITING

    London, W1G 7LJ, United Kingdom

  • The Harley Street Clinic (THSC)

    RECRUITING

    London, Other, W1G 8BJ, United Kingdom

  • The Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

  • University Health Network, Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

  • University of Colorado Hospital

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Colorado Hospital - Anschutz Cancer Pavilion (ACP)

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.