New 'Smart Bomb' drug targets tough cancers in major trial
NCT ID NCT06131840
Summary
This early-stage trial is testing the safety and dosing of an experimental drug called PF-08046050 in adults with advanced solid tumors that have returned or stopped responding to standard treatments. The drug is designed to attach to cancer cells and deliver a toxic payload directly to them. The study will enroll over 900 participants with various cancers, including colorectal, lung, stomach, and pancreatic cancers, to find the right dose and see if the drug helps control the disease.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ApoEx NKS
RECRUITINGStockholm, 17176, Sweden
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Ascires CETIR
RECRUITINGEsplugues de Llobregat, 08950, Spain
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Ascires Cetir
RECRUITINGBarcelona, 08029, Spain
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02115, United States
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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City of Hope (City of Hope National Medical Center, City of Hope Medical Center)
RECRUITINGDuarte, California, 91010, United States
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Diagnostic Centre
RECRUITINGLondon, Others, WlG 7AF, United Kingdom
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Edinburgh Cancer Centre, Western General Hospital
RECRUITINGEdinburgh, Scotland, EH4 2XU, United Kingdom
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Florida Cancer Specialists
RECRUITINGOrlando, Florida, 32827, United States
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Gustave Roussy
RECRUITINGVillejuif, 94800, France
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Hospital Universitario HM Sanchinarro-CIOCC-START Madrid
RECRUITINGMadrid, 28050, Spain
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IP Address: City of Hope Investigational Drug Services(IDS)
RECRUITINGDuarte, California, 91010, United States
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Institut Catala d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet)
RECRUITINGL'Hospitalet de Llobregat, Catalunya [cataluña], 08908, Spain
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Institut Gustave Roussy
RECRUITINGVillejuif, Paris, 94805, France
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Karolinska University Hospital
RECRUITINGSolna, 171 64, Sweden
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Lothian Health Board
RECRUITINGEdinburgh, EH3 9DN, United Kingdom
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Mayo Clinic
RECRUITINGScottsdale, Arizona, 85259, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Mayo Clinic Cancer Center
RECRUITINGRochester, Minnesota, 55905, United States
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Mayo Clinic Hospital
RECRUITINGPhoenix, Arizona, 85054, United States
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
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Netherlands Cancer Institute
RECRUITINGAmsterdam, 1066CX, Netherlands
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Radiology
RECRUITINGLondon, W1G 8PP, United Kingdom
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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START Midwest
RECRUITINGGrand Rapids, Michigan, 49546, United States
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START Mountain Region
RECRUITINGSalt Lake City, Utah, 84119, United States
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Sarah Cannon Research Institute - Pharmacy
RECRUITINGNashville, Tennessee, 37203, United States
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Sarah Cannon Research Institute UK
RECRUITINGLondon, W1G 6AD, United Kingdom
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Sarah Cannon Research Institute at Florida Cancer Specialists
RECRUITINGOrlando, Florida, 32827, United States
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Servicio de Farmacia ICO - Planta 0
RECRUITINGL'Hospitalet de Llobregat, 08908, Spain
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Sidney Kimmel Comprehensive Cancer at Johns Hopkins
RECRUITINGBaltimore, Maryland, 21287, United States
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South Texas Accelerated Research Therapeutics Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
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South Texas Accelerated Research Therapeutics, LLC
RECRUITINGSan Antonio, Texas, 78229, United States
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The Harley Street Clinic
RECRUITINGLondon, W1G 7LJ, United Kingdom
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The Harley Street Clinic (THSC)
RECRUITINGLondon, Other, W1G 8BJ, United Kingdom
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The Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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The Ottawa Hospital
RECRUITINGOttawa, Ontario, K1H 8L6, Canada
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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University Health Network
RECRUITINGToronto, Ontario, M5G 2C4, Canada
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University Health Network, Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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University of Colorado Hospital
RECRUITINGAurora, Colorado, 80045, United States
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University of Colorado Hospital - Anschutz Cancer Pavilion (ACP)
RECRUITINGAurora, Colorado, 80045, United States
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Western General Hospital
RECRUITINGEdinburgh, EH4 2XU, United Kingdom
Conditions
Explore the condition pages connected to this study.