First human tests begin for experimental cancer drug targeting multiple tumor types

NCT ID NCT05983133

Summary

This early-stage study is testing a new drug called PF-08046052/SGN-EGFRd2 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goal is to find the safest dose and understand side effects in 65 participants with specific cancers including colorectal, lung, head and neck, and pancreatic cancers. The study will also gather initial information about whether the drug might help control these cancers.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PANCREATIC DUCTAL ADENOCARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Atrium Health Wake forest Baptist

    Winston-Salem, North Carolina, 27157, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Huntsman Cancer Hospital, University of Utah

    Salt Lake City, Utah, 84112, United States

  • Huntsman Cancer Institute, University Of Utah

    Salt Lake City, Utah, 84112, United States

  • John Theurer Cancer Center at Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Karmanos Cancer Institute Weisberg Cancer Treatment Center

    Farmington Hills, Michigan, 48334, United States

  • MD Anderson Cancer Center - University of Texas

    Houston, Texas, 77030, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Moffitt Cancer Center McKinley Hospital

    Tampa, Florida, 33612, United States

  • Providence Cancer Institute Franz Clinic

    Portland, Oregon, 97213, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Ronald Reagan UCLA Medical Center

    Los Angeles, California, 90095, United States

  • Santa Monica UCLA Medical Center & Orthopaedic Hospital

    Santa Monica, California, 90404, United States

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UCLA Hematology/Oncology

    Los Angeles, California, 90095, United States

  • UCLA Hematology/Oncology - Santa Monica

    Santa Monica, California, 90404, United States

  • University College London Hospital, NIHR UCLH Clinical Research Facility

    London, W1T 7HA, United Kingdom

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Utah

    Salt Lake City, Utah, 84112, United States

  • Wake Forest Baptist Medical Center / Wake Forest University

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.