First human trial of artificial bypass graft begins
NCT ID NCT04545112
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This early study tests a new synthetic blood vessel (XABG) for coronary artery bypass surgery in 20 people with multi-vessel heart disease. The graft is designed to work like a natural artery. Researchers are checking if it stays open and is safe in the first 30 days. This is a first step to see if the idea is feasible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
synthetic coronary artery bypass graft (XABG)
What this could lead to
If successful, this could provide a new option for bypass surgery, especially for patients who lack healthy veins for grafting.
What could go wrong
This is a very early, small study with only 20 participants. The graft may not stay open or could cause complications. Much more testing is needed.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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John Paul II Hospital Krakow
Krąków, Poland
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Medicover Hospital
Warsaw, Poland
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UZ Leuven
Leuven, Belgium
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Vilnius University Hospital Santaros Klinikos
Vilnius, Lithuania