Major trial tests promising new weapons against aggressive breast cancer

NCT ID NCT06103864

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large international study is testing whether new drug combinations work better than current standard treatments for advanced triple-negative breast cancer. Researchers will compare two experimental treatments against standard chemotherapy in 625 patients whose cancer has returned or spread. The main goal is to see if the new treatments help patients live longer without their cancer getting worse, while also tracking side effects and quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Research Site
RECRUITING

Daphne, Alabama, 36526, United States
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RECRUITING

Springdale, Arkansas, 72762, United States
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WITHDRAWN

Duarte, California, 91010, United States
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RECRUITING

Glendale, California, 91204, United States
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RECRUITING

Sacramento, California, 95817, United States
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WITHDRAWN

Santa Rosa, California, 95403, United States
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Aurora, Colorado, 80012, United States
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RECRUITING

New Haven, Connecticut, 06510, United States
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WITHDRAWN

Jacksonville, Florida, 32256, United States
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RECRUITING

Miami, Florida, 33176, United States
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WITHDRAWN

Palm Bay, Florida, 32909, United States
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RECRUITING

Plantation, Florida, 33324, United States
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SUSPENDED

Atlanta, Georgia, 30318, United States
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WITHDRAWN

Honolulu, Hawaii, 96819, United States
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RECRUITING

Chicago, Illinois, 60637, United States
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WITHDRAWN

Decatur, Illinois, 62526, United States
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Elmhurst, Illinois, 60126, United States
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Naperville, Illinois, 60540, United States
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WITHDRAWN

New Albany, Indiana, 47150, United States
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RECRUITING

Des Moines, Iowa, 50309, United States
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WITHDRAWN

Lexington, Kentucky, 40503, United States
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Louisville, Kentucky, 40202, United States
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WITHDRAWN

Louisville, Kentucky, 40207, United States
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WITHDRAWN

Baton Rouge, Louisiana, 70808, United States
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RECRUITING

Baton Rouge, Louisiana, 70809, United States
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WITHDRAWN

Baltimore, Maryland, 21215, United States
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RECRUITING

Columbia, Maryland, 21044, United States
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WITHDRAWN

Boston, Massachusetts, 02111, United States
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WITHDRAWN

Worcester, Massachusetts, 01655, United States
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RECRUITING

Detroit, Michigan, 48201, United States
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WITHDRAWN

Grand Rapids, Michigan, 49503, United States
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RECRUITING

Saint Paul, Minnesota, 55109, United States
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WITHDRAWN

Hattiesburg, Mississippi, 39401, United States
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RECRUITING

St Louis, Missouri, 63129, United States
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RECRUITING

Albuquerque, New Mexico, 87109, United States
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WITHDRAWN

Albany, New York, 12206, United States
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RECRUITING

New York, New York, 10065, United States
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RECRUITING

Stony Brook, New York, 11794-7263, United States
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Cincinnati, Ohio, 45219, United States
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Cincinnati, Ohio, 45245, United States
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RECRUITING

Cleveland, Ohio, 44195, United States
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WITHDRAWN

York, Pennsylvania, 17403, United States
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RECRUITING

Providence, Rhode Island, 02903, United States
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RECRUITING

Chattanooga, Tennessee, 37404, United States
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RECRUITING

Nashville, Tennessee, 37203, United States
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WITHDRAWN

Dallas, Texas, 75230, United States
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RECRUITING

Dallas, Texas, 75246, United States
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WITHDRAWN

Dallas, Texas, 75246, United States
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RECRUITING

El Paso, Texas, 79902, United States
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WITHDRAWN

Flower Mound, Texas, 75028, United States
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WITHDRAWN

Fort Worth, Texas, 76104, United States
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WITHDRAWN

Houston, Texas, 77054, United States
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WITHDRAWN

Houston, Texas, 77090, United States
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WITHDRAWN

Houston, Texas, 77098, United States
Research Site
WITHDRAWN

Kingwood, Texas, 77339, United States
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WITHDRAWN

McKinney, Texas, 75071, United States
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RECRUITING

Sugar Land, Texas, 77479, United States
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RECRUITING

Charlottesville, Virginia, 22903, United States
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Fairfax, Virginia, 22031, United States
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Midlothian, Virginia, 23114, United States
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Norfolk, Virginia, 23502, United States
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RECRUITING

Roanoke, Virginia, 24014, United States
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RECRUITING

Tacoma, Washington, 98405, United States
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WITHDRAWN

Madison, Wisconsin, 53792, United States
Research Site
RECRUITING

CABA, 1414, Argentina
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RECRUITING

CABA, 1425, Argentina
Research Site
RECRUITING

CABA, C1113AAE, Argentina
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WITHDRAWN

CABA, C1425, Argentina
Research Site
RECRUITING

Ciudad Autónoma Buenos Aires, C1430EFA, Argentina
Research Site
RECRUITING

Ciudad de Buenos Aires, C1015ABO, Argentina
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RECRUITING

Rosario, 2000, Argentina
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WITHDRAWN

San Nicolás de los Arroyos, B2900, Argentina
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RECRUITING

Camperdown, 2050, Australia
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RECRUITING

Darlinghurst, 2010, Australia
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RECRUITING

Heidelberg, 3084, Australia
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RECRUITING

Melbourne, 3000, Australia
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RECRUITING

Nedlands, 6009, Australia
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WITHDRAWN

Waratah, 2298, Australia
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RECRUITING

Barretos, 14784-400, Brazil
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RECRUITING

Curitiba, 80730-150, Brazil
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RECRUITING

Florianópolis, 88034-000, Brazil
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RECRUITING

Goiânia, 74000-000, Brazil
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RECRUITING

Itajaí, 88301-220, Brazil
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RECRUITING

Porto Alegre, 90035-003, Brazil
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RECRUITING

Recife, 52010-075, Brazil
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RECRUITING

São Paulo, 01246-000, Brazil
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RECRUITING

São Paulo, 01317-001, Brazil
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RECRUITING

Teresina, 64049-200, Brazil
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RECRUITING

Barrie, Ontario, L4M 6M2, Canada
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Hamilton, Ontario, L8V 5C2, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Greenfield Park, Quebec, J4V 2H1, Canada
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Montreal, Quebec, H2X 0A9, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Québec, Quebec, G1S 4L8, Canada
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Regina, Saskatchewan, S4T 7T1, Canada
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RECRUITING

Saskatoon, Saskatchewan, S7N 4H4, Canada
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RECRUITING

Anyang, 455000, China
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RECRUITING

Beijing, 100044, China
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RECRUITING

Beijing, 100142, China
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RECRUITING

Bengbu, 233004, China
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RECRUITING

Changchun, 130021, China
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RECRUITING

Changsha, 410008, China
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RECRUITING

Changsha, 410013, China
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RECRUITING

Chengdu, 610000, China
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RECRUITING

Chengdu, 610041, China
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WITHDRAWN

Chongqing, 400030, China
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RECRUITING

Fuzhou, 350014, China
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RECRUITING

Guangzhou, 510060, China
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RECRUITING

Guangzhou, 510120, China
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RECRUITING

Guangzhou, 510700, China
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RECRUITING

Hangzhou, 310009, China
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RECRUITING

Hangzhou, 310016, China
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RECRUITING

Hangzhou, 310022, China
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RECRUITING

Harbin, 150081, China
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RECRUITING

Hefei, 230031, China
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RECRUITING

Jinan, 250021, China
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NOT_YET_RECRUITING

Meizhou, 514031, China
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RECRUITING

Nanchang, 330009, China
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RECRUITING

Nanjing, 2100008, China
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RECRUITING

Nanjing, 210009, China
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RECRUITING

Nanning, 530021, China
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RECRUITING

Shandong, China
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RECRUITING

Shanghai, 200025, China
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COMPLETED

Shanghai, 200080, China
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RECRUITING

Shenyang, 110004, China
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RECRUITING

Tianjin, 300000, China
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RECRUITING

Wenzhou, 325000, China
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RECRUITING

Wuhan, 430022, China
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RECRUITING

Wuhan, 430079, China
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RECRUITING

Xi'an, 710061, China
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RECRUITING

Xiamen, 361003, China
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RECRUITING

Xintai, 54031, China
Research Site
RECRUITING

Xuzhou, 221009, China
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RECRUITING

Zhanjiang, 524003, China
Research Site
RECRUITING

Zhengzhou, 450008, China
Research Site
RECRUITING

Zhengzhou, 450052, China
Research Site
RECRUITING

Lille, 59000, France
Research Site
RECRUITING

Lyon, 69373, France
Research Site
RECRUITING

Montpellier, 34298, France
Research Site
RECRUITING

Paris, 75020, France
Research Site
RECRUITING

Saint-Herblain, 44805, France
Research Site
RECRUITING

Toulouse, 31059, France
Research Site
RECRUITING

Vandœuvre-lès-Nancy, 54511, France
Research Site
RECRUITING

Villejuif, 94800, France
Research Site
WITHDRAWN

Düsseldorf, 40479, Germany
Research Site
WITHDRAWN

Essen, 45136, Germany
Research Site
WITHDRAWN

Georgsmarienhütte, 49124, Germany
Research Site
WITHDRAWN

Hamburg, 20357, Germany
Research Site
WITHDRAWN

Hanover, 30625, Germany
Research Site
WITHDRAWN

Heidelberg, 69120, Germany
Research Site
WITHDRAWN

Heilbronn, 74078, Germany
Research Site
WITHDRAWN

Leipzig, 04103, Germany
Research Site
RECRUITING

Hong Kong, 999077, Hong Kong
Research Site
NOT_YET_RECRUITING

Hong Kong, 999077, Hong Kong
Research Site
NOT_YET_RECRUITING

Hong Kong, Hong Kong
Research Site
RECRUITING

Shatin, 00000, Hong Kong
Research Site
WITHDRAWN

Calicut, 673601, India
Research Site
RECRUITING

Chennai, 600031, India
Research Site
NOT_YET_RECRUITING

Jaipur, 302004, India
Research Site
WITHDRAWN

Kochi, 682027, India
Research Site
WITHDRAWN

Kolkata, 700160, India
Research Site
RECRUITING

Marg Jaipur, 302004, India
Research Site
RECRUITING

Mohali, 160055, India
Research Site
RECRUITING

Mysuru, 570017, India
Research Site
RECRUITING

Nagpur, 440001, India
Research Site
RECRUITING

Nashik, 422009, India
Research Site
RECRUITING

New Delhi, 110075, India
Research Site
RECRUITING

New Delhi, 11029, India
Research Site
RECRUITING

Puducherry, 605006, India
Research Site
RECRUITING

Surat, 395002, India
Research Site
RECRUITING

Thiruvananthapuram, 695011, India
Research Site
RECRUITING

Vadodara, 391760, India
Research Site
WITHDRAWN

Visakhapatnam, 530053, India
Research Site
RECRUITING

Bergamo, 24127, Italy
Research Site
RECRUITING

Empoli, 50053, Italy
Research Site
RECRUITING

Milan, 20132, Italy
Research Site
RECRUITING

Milan, 20141, Italy
Research Site
WITHDRAWN

Modena, 41124, Italy
Research Site
RECRUITING

Naples, 80131, Italy
Research Site
RECRUITING

Padua, 35128, Italy
Research Site
RECRUITING

Reggio Emilia, 42123, Italy
Research Site
RECRUITING

Roma, 00168, Italy
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RECRUITING

Rozzano, 20089, Italy
Research Site
RECRUITING

Akashi-shi, 673-8558, Japan
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RECRUITING

Bunkyō City, 113-8431, Japan
Research Site
RECRUITING

Bunkyō City, 113-8677, Japan
Research Site
RECRUITING

Chiba, 260-8717, Japan
Research Site
RECRUITING

Chūōku, 104-0045, Japan
Research Site
RECRUITING

Fukuoka, 811-1395, Japan
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RECRUITING

Fukushima, 960-1295, Japan
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RECRUITING

Gifu, 501-1194, Japan
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RECRUITING

Hidaka-shi, 350-1298, Japan
Research Site
RECRUITING

Hiroshima, 730-8518, Japan
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RECRUITING

Hiroshima, 734-8551, Japan
Research Site
RECRUITING

Isehara-shi, 259-1193, Japan
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RECRUITING

Kamogawa-shi, 296-8602, Japan
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RECRUITING

Kashiwa, 277-8577, Japan
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RECRUITING

Kitaadachi-gun, 362-0806, Japan
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RECRUITING

Kōtoku, 135-8550, Japan
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RECRUITING

Kumamoto, 860-8556, Japan
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RECRUITING

Kurume-shi, 830-0011, Japan
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RECRUITING

Matsuyama, 791-0280, Japan
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RECRUITING

Nagoya, 466-8560, Japan
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RECRUITING

Nagoya, 467-8602, Japan
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RECRUITING

Niigata, 951-8566, Japan
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RECRUITING

Nishinomiya-shi, 663-8501, Japan
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RECRUITING

Okayama, 700-8558, Japan
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RECRUITING

Osaka, 541-8567, Japan
Research Site
RECRUITING

Osakasayama-shi, 589-8511, Japan
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RECRUITING

Ota-shi, 373-8550, Japan
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RECRUITING

Sapporo, 003-0804, Japan
Research Site
RECRUITING

Sendai, 980-8574, Japan
Research Site
RECRUITING

Shinagawa-ku, 142-8666, Japan
Research Site
RECRUITING

Shinjuku-ku, 160-0023, Japan
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RECRUITING

Shinjuku-ku, 162-8655, Japan
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RECRUITING

Tsu, 514-8507, Japan
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RECRUITING

Tsukuba, 305-8577, Japan
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RECRUITING

Yokohama, 241-8515, Japan
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RECRUITING

CD Mexico, 04980, Mexico
Research Site
RECRUITING

Guadalajara, 44638, Mexico
Research Site
WITHDRAWN

Guadalajara, 44670, Mexico
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RECRUITING

Mexico City, 0 3100, Mexico
Research Site
RECRUITING

México, 04700, Mexico
Research Site
RECRUITING

México, 6760, Mexico
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RECRUITING

Tuxtla Gutiérrez, 29090, Mexico
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RECRUITING

Bacolod, 6100, Philippines
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RECRUITING

Cebu City, 6000, Philippines
Research Site
RECRUITING

City of Muntinlupa, 1780, Philippines
Research Site
RECRUITING

Manila, 1000, Philippines
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RECRUITING

Quezon City, 1112, Philippines
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RECRUITING

San Juan City, 1502, Philippines
Research Site
WITHDRAWN

Bialystok, 15-027, Poland
Research Site
WITHDRAWN

Bydgoszcz, 85-796, Poland
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NOT_YET_RECRUITING

Gdansk, 80-952, Poland
Research Site
WITHDRAWN

Gdynia, 81-519, Poland
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WITHDRAWN

Konin, 62-500, Poland
Research Site
WITHDRAWN

Krakow, 31-115, Poland
Research Site
NOT_YET_RECRUITING

Krakow, 31-501, Poland
Research Site
WITHDRAWN

Legnica, 59-220, Poland
Research Site
NOT_YET_RECRUITING

Lodz, 90-302, Poland
Research Site
WITHDRAWN

Lublin, 20-090, Poland
Research Site
WITHDRAWN

Przemyśl, 37-700, Poland
Research Site
NOT_YET_RECRUITING

Warsaw, 02-781, Poland
Research Site
WITHDRAWN

Wroclaw, 53-413, Poland
Research Site
WITHDRAWN

Singapore, 119228, Singapore
Research Site
RECRUITING

Singapore, 169610, Singapore
Research Site
RECRUITING

Singapore, 217562, Singapore
Research Site
RECRUITING

Singapore, 308433, Singapore
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RECRUITING

Cape Town, 7570, South Africa
Research Site
RECRUITING

Johannesburg, 2013, South Africa
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RECRUITING

Johannesburg, 2193, South Africa
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RECRUITING

Johannesburg, 2196, South Africa
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RECRUITING

Paarl, 7646, South Africa
Research Site
RECRUITING

Pretoria, 0081, South Africa
Research Site
COMPLETED

Busan, 49241, South Korea
Research Site
RECRUITING

Daegu, 41404, South Korea
Research Site
RECRUITING

Goyang-si, 10408, South Korea
Research Site
RECRUITING

Seongnam-si, 13620, South Korea
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RECRUITING

Seoul, 02841, South Korea
Research Site
RECRUITING

Seoul, 03080, South Korea
Research Site
RECRUITING

Seoul, 03722, South Korea
Research Site
RECRUITING

Seoul, 05505, South Korea
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RECRUITING

Seoul, 06273, South Korea
Research Site
RECRUITING

Seoul, 06351, South Korea
Research Site
RECRUITING

Seoul, 06591, South Korea
Research Site
WITHDRAWN

Barcelona, 08028, Spain
Research Site
RECRUITING

Barcelona, 8035, Spain
Research Site
RECRUITING

Granada, 18016, Spain
Research Site
RECRUITING

Hospitalet deLlobregat, 08907, Spain
Research Site
RECRUITING

Madrid, 28007, Spain
Research Site
WITHDRAWN

Madrid, 28034, Spain
Research Site
RECRUITING

Pamplona, 31008, Spain
Research Site
RECRUITING

Santander, 39008, Spain
Research Site
RECRUITING

Hsinchu, 300, Taiwan
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RECRUITING

Kaohsiung City, 80756, Taiwan
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RECRUITING

Taichung, 40447, Taiwan
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RECRUITING

Tainan, 704, Taiwan
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RECRUITING

Taipei, 100, Taiwan
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RECRUITING

Taipei, 10449, Taiwan
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RECRUITING

Taipei, 11259, Taiwan
Research Site
RECRUITING

Taipei, 112, Taiwan
Research Site
RECRUITING

Taoyuan District, 333, Taiwan
Research Site
RECRUITING

Bangkok, 10210, Thailand
Research Site
RECRUITING

Bangkok, 10330, Thailand
Research Site
RECRUITING

Bangkok, 10400, Thailand
Research Site
NOT_YET_RECRUITING

Bangkok, 10700, Thailand
Research Site
RECRUITING

Chiang Mai, 50200, Thailand
Research Site
RECRUITING

Dusit, 10300, Thailand
Research Site
RECRUITING

Khon Kaen, 40002, Thailand
Research Site
RECRUITING

Songkhla, 90110, Thailand
Research Site
RECRUITING

Ankara, 06520, Turkey (Türkiye)
Research Site
RECRUITING

Ankara, 6200, Turkey (Türkiye)
Research Site
RECRUITING

Besevler Ankara, Turkey (Türkiye)
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NOT_YET_RECRUITING

Istanbul, 34010, Turkey (Türkiye)
Research Site
WITHDRAWN

Izmir, 35575, Turkey (Türkiye)
Research Site
RECRUITING

Küçükçekmece, 34295, Turkey (Türkiye)
Research Site
RECRUITING

Samsun, 55200, Turkey (Türkiye)
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RECRUITING

Cardiff, CF14 2TL, United Kingdom
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RECRUITING

Chelsea, SW3 6JJ, United Kingdom
Research Site
RECRUITING

Leicester, Le5 4PW, United Kingdom
Research Site
SUSPENDED

Liverpool, L7 8YA, United Kingdom
Research Site
RECRUITING

London, EC1A 7BE, United Kingdom
Research Site
WITHDRAWN

London, SW17 0QT, United Kingdom
Research Site
SUSPENDED

Oxford, OX3 7LE, United Kingdom
Research Site
SUSPENDED

Surrey, GU2 7XX, United Kingdom
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RECRUITING

Sutton, SM2 5PT, United Kingdom
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RECRUITING

Taunton, TA1 5DA, United Kingdom
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NOT_YET_RECRUITING

Da Nang, 550000, Vietnam
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RECRUITING

Hanoi, 100000, Vietnam
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RECRUITING

Ho Chi Minh City, 700000, Vietnam
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RECRUITING

Hồ Chí Minh, 700000, Vietnam
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RECRUITING

Huế, 530000, Vietnam
Research Site
RECRUITING

Việt Trì, 35000, Vietnam
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RECRUITING

Vinh, 460000, Vietnam

Conditions

Explore the condition pages connected to this study.

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