New hope for advanced breast cancer? trial tests potential cheaper alternative

NCT ID NCT07386938

Ongoing Disease control Sponsor: R-Pharm Source: ClinicalTrials.gov ↗

Summary

This study is testing if a new drug called RPH-051 works as well as the established drug Perjeta (pertuzumab) for controlling advanced HER2-positive breast cancer. About 246 patients with metastatic or locally advanced cancer will receive either RPH-051 or Perjeta, combined with two other standard drugs (trastuzumab and docetaxel), to see which is better at shrinking tumors and controlling the disease. The main goal is to see if the new drug is not worse than the current standard, which could provide a new treatment option.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Branch of the Limited Liability Company "Hadassah Medical Ltd." (LLC Branch "Hadassah Medical")

Moscow, 121205, Russia
Budgetary Healthcare Institution of Omsk Region "Clinical Oncology Dispensary"

Omsk, 644046, Russia
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)

Moscow, 119435, Russia
Federal State Autonomous Institution "National Medical Research Center 'Medical and Rehabilitation Center'" of the Ministry of Health of the Russian Federation

Moscow, 125367, Russia
Federal State Budgetary Educational Institution of Higher Education "Siberian State Medical University" of the Ministry of Health of the Russian Federation

Tomsk, 634028, Russia
Federal State Budgetary Healthcare Institution "Clinical Hospital No. 8 of the Federal Medical-Biological Agency" (FSBHI CH No. 8 FMBA)

Obninsk, 249030, Russia
Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation

Moscow, 115478, Russia
Federal State Budgetary Institution "N.N. Petrov National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation

Moscow, 197758, Russia
Federal State Budgetary Institution "N.N. Petrov National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation

Saint Petersburg, 197758, Russia
Federal State Budgetary Institution "National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation

Rostov-on-Don, 344037, Russia
Federal State Budgetary Institution "National Medical Research Center of Radiology" of the Ministry of Health of the Russian Federation

Obninsk, 125284, Russia
Federal State Budgetary Scientific Institution "Tomsk National Research Medical Center of the Russian Academy of Sciences" (FSBSI "Tomsk NRMC of the Russian Academy of Sciences")

Tomsk, 634045, Russia
Joint-Stock Company "Medsi Group of Companies" (JSC "Medsi Group of Companies")

Moscow, 143442, Russia
Joint-Stock Company "Modern Medical Technologies"

Saint Petersburg, 190121, Russia
Kirov Regional State Clinical Budgetary Healthcare Institution "Center of Oncology and Medical Radiology"

Kirov, 610045, Russia
Limited Liability Company "EuroCityClinic"

Saint Petersburg, 197022, Russia
Limited Liability Company "Novaya Liniya"

Nal'chik, 360003, Russia
Limited Liability Company "RESEARCH LAB"

Moscow, 127521, Russia
Limited Liability Company Medical and Sanitary Unit "Clinician-Pretor Clinic"

Novosibirsk, 630091, Russia
Private Healthcare Institution "RZD-Medicine Clinical Hospital of Chelyabinsk"

Chelyabinsk, 454048, Russia
Private Medical Institution "Euromedservice" (PMI "Euromedservice")

Moscow, Russia
Regional Budgetary Healthcare Institution "Ivanovo Regional Oncology Dispensary" (RBHI "IvOOD")

Ivanovo, 153040, Russia
Regional Budgetary Healthcare Institution "Kursk Oncology Research and Clinical Center named after G.E. Ostroverhov"

Kursk, Kursk Oblast, 305524, Russia
Regional State Budgetary Healthcare Institution "Altai Regional Oncology Dispensary"

Barnaul, 656045, Russia
Regional State Budgetary Healthcare Institution "Krasnoyarsk Regional Clinical Oncology Dispensary named after A.I. Kryzhanovsky"

Krasnoyarsk, 660133, Russia
Regional State Budgetary Healthcare Institution "Smolensk Regional Oncology Clinical Dispensary"

Smolensk, 214000, Russia
Saint Petersburg State Budgetary Healthcare Institution "City Clinical Oncology Dispensary" (SPB SBHI CCOD)

Saint Petersburg, 198255, Russia
State Autonomous Healthcare Institution "Republican Clinical Oncology Dispensary of the Ministry of Health of the Republic of Tatarstan named after Professor M.Z. Sigal"

Kazan', 420029, Russia
State Autonomous Healthcare Institution "Republican Clinical Oncology Dispensary" of the Ministry of Health of the Republic of Bashkortostan

Ufa, 450054, Russia
State Autonomous Healthcare Institution of Sverdlovsk Region "Sverdlovsk Regional Oncology Dispensary"

Yekaterinburg, 620036, Russia
State Autonomous Healthcare Institution of the Nizhny Novgorod Region "Research Institute of Clinical Oncology 'Nizhny Novgorod Regional Clinical Oncology Dispensary'"

Nizhny Novgorod, 603081, Russia
State Budgetary Healthcare Institution "Kuzbass Clinical Oncology Dispensary named after M.S. Rappoport" (SBHI "KCOD")

Kemerovo, 650036, Russia
State Budgetary Healthcare Institution "Leningrad Regional Clinical Hospital" (SBHI "LOKH")

Kuz'molovskiy, Leningradskaya Oblast', 188663, Russia
State Budgetary Healthcare Institution "St. Petersburg Clinical Scientific and Practical Center for Specialized Medical Care (Oncology) named after N.P. Napalkov"

Saint Petersburg, 197758, Russia
State Budgetary Healthcare Institution "Volgograd Regional Clinical Oncology Dispensary"

Volgograd, 400138, Russia
State Budgetary Healthcare Institution of Arkhangelsk Region "Arkhangelsk Clinical Oncology Dispensary"

Arkhangelsk, 163045, Russia
State Budgetary Healthcare Institution of Kaluga Region "Kaluga Regional Clinical Oncology Dispensary"

Kaluga, 248007, Russia
State Budgetary Healthcare Institution of Perm Krai "Perm Krai Oncology Dispensary"

Perm, 614066, Russia
State Budgetary Healthcare Institution of Stavropol Krai "Pyatigorsk Interdistrict Oncology Dispensary"

Pyatigorsk, 357500, Russia
State Budgetary Healthcare Institution of Yaroslavl Region "Regional Clinical Oncology Hospital"

Yaroslavl, 150054, Russia
State Budgetary Healthcare Institution of the City of Moscow "City Clinical Hospital named after S.S. Yudin" of the Moscow Department of Healthcare

Moscow, 129090, Russia
State Budgetary Healthcare Institution of the City of Moscow "Moscow Clinical Scientific and Practical Center named after A.S. Loginov of the Moscow Department of Healthcare"

Moscow, Russia
State Budgetary Healthcare Institution of the City of Moscow "Moscow Multidisciplinary Clinical Center 'Kommunarka' of the Moscow Department of Healthcare" (SBHI "MMCC 'Kommunarka'")

Moscow, 108814, Russia
State Healthcare Institution "Regional Clinical Oncology Dispensary" (SHI "RCOD")

Saratov, 410053, Russia
State Healthcare Institution "Tula Regional Clinical Oncology Dispensary" (SHI "TRCOD")

Tula, 300039, Russia

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED BREAST CANCER METASTATIC BREAST CANCER