Blood test may replace biopsy for breast cancer subtyping

NCT ID NCT07574749

First seen May 09, 2026 · Last updated Jun 23, 2026 · Updated 8 times

Summary

This study is testing a new blood test that looks for tiny particles from breast cancer cells, called small extracellular vesicles (sEVs), to determine the cancer's molecular subtype. The goal is to see if this test is as accurate as the standard tissue biopsy. Researchers will compare results from the blood test with those from traditional pathology in 1500 people with advanced breast cancer. If it works, this could lead to a quicker, less invasive way to guide treatment decisions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

diagnostic test using small extracellular vesicles (sEVs) on a microchip

What this could lead to

If successful, this could provide a faster, less invasive way to determine breast cancer subtypes, helping doctors choose the most effective treatment for each patient.

What could go wrong

This is an early-phase exploratory study, so the test may not prove accurate enough for routine use. It is also limited to patients with advanced breast cancer, so results may not apply to earlier stages.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.