First patients receive new experimental drug targeting genetic cause of ALS
NCT ID NCT06351592
Summary
This is the first study to test an experimental drug called ALN-SOD in people with ALS caused by a specific change in the SOD1 gene. The main goal is to check the drug's safety and how well it's tolerated when given via spinal injection. Researchers will also measure how the drug affects certain disease markers in the blood and spinal fluid, and look for any early signs of effect on ALS symptoms.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Concord Repatriation General Hospital
RECRUITINGConcord, New South Wales, 2139, Australia
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Hanyang University Seoul Hospital
RECRUITINGSeoul, 04763, South Korea
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Hokkaido University Hospital
RECRUITINGSapporo, Hokkaido, 060-8648, Japan
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KU Leuven
RECRUITINGLeuven, Vlaams-Brabant, 3000, Belgium
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Kaohsiung Chang Gung Memorial Hospital
RECRUITINGKaohsiung City, 83301, Taiwan
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Kyoto University Hospital
RECRUITINGKyoto, 606-8507, Japan
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Macquarie University
RECRUITINGSydney, New South Wales, 2109, Australia
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Montreal Neurological Institute and Hospital
RECRUITINGMontreal, Quebec, H3A 2B4, Canada
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Seoul National University Hospital
RECRUITINGSeoul, 3080, South Korea
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Sunnybrook Research Institute
RECRUITINGToronto, Ontario, M4N 3M5, Canada
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Sunshine Coast University Hospital
RECRUITINGBirtinya, Queensland, 4575, Australia
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Taipei Veterans General Hospital
RECRUITINGTaipei, 11211, Taiwan
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Toho University Omori Medical Center
RECRUITINGŌta-ku, Tokyo, 143-8541, Japan
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Tokushima University Hospital
RECRUITINGTokushima, Tokushima, 770-0042, Japan
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University Hospital - London Health Sciences Centre
RECRUITINGLondon, Ontario, N6A 5A5, Canada
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University of Alberta Hospital, Edmonton, Division of Neurology
RECRUITINGEdmonton, Alberta, T6G 2G3, Canada
Conditions
Explore the condition pages connected to this study.