Zapping a nerve to fight sepsis: new trial tests simple ear stimulation

NCT ID NCT03992378

First seen Apr 02, 2026 · Last updated May 12, 2026 · Updated 5 times

Summary

This study tests whether stimulating a nerve in the ear (vagus nerve) can reduce inflammation and improve heart function in people with septic shock, a life-threatening condition. About 34 participants will receive either active or sham stimulation for 4 hours, alongside standard care. The goal is to see if this approach lowers inflammatory markers and improves organ failure scores, paving the way for a larger trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Oklahoma Health Sciences Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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