Brain training shows promise for tic control in teens

NCT ID NCT05558566

Recruiting now Symptom relief Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether real-time fMRI neurofeedback can help teens aged 10-16 with Tourette Syndrome reduce their tics. Participants learn to control activity in a brain region linked to tics by watching their own brain activity on a screen. The trial compares this to a control group that receives feedback from a different brain area. The goal is to see if this training leads to lasting symptom improvement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: real-time fMRI neurofeedback
What this could lead to: If it works, this could offer a non-drug, non-invasive way for teens to gain some control over their tics.
What could go wrong: This is an early-stage study with only 64 participants. The effect may be small, temporary, or not work for everyone. It requires multiple fMRI sessions, which may not be practical long-term.

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Conditions

The condition(s) this trial relates to.

chronic tic disorder Tourette syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOURETTE SYNDROME IN ADOLESCENCE

Contacts and locations

Locations

Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06520, United States

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