Zapping a nerve in the forehead could reveal how brain and body talk

NCT ID NCT07662291

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether stimulating a nerve in the forehead at different speeds changes how the brain and the body's automatic systems (like breathing and heart rate) work together. Twenty-five healthy adults will receive mild electrical pulses at 2Hz, 120Hz, or a fake (sham) stimulation while inside an MRI scanner. Researchers will watch brain activity and body signals to see which frequency has the strongest effect.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcutaneous trigeminal nerve stimulation (eTNS)

What this could lead to

If successful, this could help design better nerve stimulation therapies for conditions like anxiety, chronic pain, or heart rate disorders.

What could go wrong

This is a small, early-stage study in healthy volunteers, so results may not apply to people with medical conditions. The effects may be subtle or not clinically meaningful.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xidian University

    RECRUITING

    Xi'an, Shaanxi, 71000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••