New injection could cut Post-Surgery painkiller use

NCT ID NCT07174440

Recruiting now Symptom relief Sponsor: University Hospitals Cleveland Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a numbing injection (erector spinae plane block) given before lumbar spine fusion surgery. The injection contains ropivacaine, dexmedetomidine, and a contrast dye. Researchers will measure how much pain relief it provides and how far the medication spreads. 32 adults scheduled for spine fusion will participate. The goal is to improve recovery and reduce the need for opioid painkillers after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine, dexmedetomidine, and iohexol
What this could lead to: If it works, this could provide a better way to control pain after spine surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, early-stage study with only 32 participants. The results may not apply to everyone, and there are risks like allergic reactions or the block not working well.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAIN

Contacts and locations

Locations

University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States

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