New injection could cut Post-Surgery painkiller use

NCT ID NCT07174440

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a numbing injection (erector spinae plane block) given before lumbar spine fusion surgery. The injection contains ropivacaine, dexmedetomidine, and a contrast dye. Researchers will measure how much pain relief it provides and how far the medication spreads. 32 adults scheduled for spine fusion will participate. The goal is to improve recovery and reduce the need for opioid painkillers after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ropivacaine, dexmedetomidine, and iohexol

What this could lead to

If it works, this could provide a better way to control pain after spine surgery, reducing the need for strong painkillers.

What could go wrong

This is a small, early-stage study with only 32 participants. The results may not apply to everyone, and there are risks like allergic reactions or the block not working well.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••