New nerve block could slash opioid use after back surgery

NCT ID NCT07334288

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an ultrasound-guided nerve block, given before lumbar spine surgery, can reduce pain and the need for opioid painkillers afterward. Fifty adults scheduled for back surgery will be randomly assigned to receive either the nerve block plus standard pain management or standard care alone. Researchers will measure total opioid use in the first 24 hours, pain levels, and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bupivacaine and Epinephrine (nerve block injection)

What this could lead to

If it works, this could offer a better way to manage pain after back surgery, reducing the need for strong painkillers like opioids.

What could go wrong

This is a small, early-stage trial with only 50 participants. The nerve block may not provide significant extra pain relief, and there are rare risks like allergic reaction or nerve damage from the injection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clínica Universidad de los Andes, Chile

    RECRUITING

    Santiago, Santiago Metropolitan, 171571, Chile

    Contact Phone: •••-•••-•••• Email: •••••@•••••