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Can a single nerve block cut opioid use after hernia surgery?

NCT ID NCT07878936

NEW Symptom relief Sponsor: Marmara University Pendik Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 16, 2026 · Last updated Oct 16, 2026

Summary

Researchers are testing whether an ultrasound-guided quadro-iliac plane block reduces opioid use and pain after laparoscopic inguinal hernia repair. The trial enrolls 64 adults aged 18 to 65 who are scheduled for elective unilateral surgery under general anesthesia. All participants receive the same general anesthesia and pain relief, while half also receive the nerve block with bupivacaine. The team tracks tramadol use, pain scores, recovery quality, nausea, and time to discharge over the first 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an ultrasound-guided quadro-iliac plane block using bupivacaine
What this could lead to
If it works, this nerve block could become a standard option to cut opioid use and ease pain after laparoscopic hernia repair.
What could go wrong
The block may not reduce opioid needs more than standard pain relief, and it carries small risks such as bleeding, infection, or nerve irritation at the injection site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-65 years * American Society of Anesthesiologists (ASA) physical status I-III * Scheduled for elective unilateral laparoscopic inguinal hernia repair (TAPP or TEP) under general anesthesia * Written informed consent Exclusion Criteria: * Refusal to participate * Bilateral hernia repair or conversion to open surgery * Known allergy to local anesthetics or study drugs * Coagulopathy or ongoing therapeutic anticoagulation * Infection at the block site * Chronic pain or regular opioid use before surgery * Severe hepatic or renal dysfunction * Pregnancy * Inability to understand the NRS or use the PCA device

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Conditions

The condition(s) this trial relates to.

opioid abuse Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inguinal hernia unilateral Opioid use Postoperative pain

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  2. A doctor treating you

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