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Can a nerve block calm inflammation after breast cancer surgery?

NCT ID NCT07843212

Symptom relief Sponsor: Mucahide Emine Fidancı Kuas Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 25, 2026 · Last updated Sep 25, 2026

Summary

Researchers are testing whether a nerve block called the serratus posterior superior intercostal plane block can reduce inflammation and improve recovery after breast cancer surgery. The trial enrolls 80 women scheduled for breast cancer surgery under general anesthesia. Half receive the active nerve block and half receive a sham procedure. The team measures pain, need for pain medicine, nausea, hospital stay, and persistent pain at three months, along with blood markers of inflammation and immune activity.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
serratus posterior superior intercostal plane block, a nerve block given before breast cancer surgery
What this could lead to
If it works, this could give surgeons a way to ease pain and calm the body's inflammatory response after breast cancer surgery, possibly helping patients recover faster.
What could go wrong
This is a small, single-center study, so the results may not hold up in larger or more varied groups. The block may not change inflammation or pain enough to matter, and nerve blocks carry small risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18 to 85 years. * Scheduled for elective breast cancer surgery under general anesthesia. * American Society of Anesthesiologists (ASA) physical status I-III. * Able to provide written informed consent. Exclusion Criteria: * Refusal to participate or inability to provide informed consent. * Allergy or contraindication to the study local anesthetic. * Coagulopathy or ongoing anticoagulant treatment contraindicating regional anesthesia. * Infection at the planned injection site. * Pre-existing chronic pain condition or regular opioid use. * Inability to communicate pain scores or comply with study assessments.

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Conditions

The condition(s) this trial relates to.

age related macular degeneration 10 breast cancer breast neoplasm Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Serratus posterior superior intercostal plane block (spsipb) Toll-like receptors

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Hitit University Erol Olçok Training and Research Hospital

    RECRUITING

    Çorum, Çorum, 19040, Turkey (Türkiye)

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