Can a double nerve block silence the deep pain after bariatric surgery?
NCT ID NCT06973122
First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time
Summary
This trial tests whether combining two nerve-block techniques—one targeting the stomach area and another the abdominal wall—can better control visceral pain after laparoscopic bariatric surgery. Visceral pain is a deep, internal discomfort that often causes nausea and doesn't respond well to standard painkillers. The study will enroll 127 adults with obesity undergoing bariatric surgery, comparing the combined block to a standard abdominal wall block alone. Researchers will measure pain scores, opioid use, and nausea in the early post-surgery period.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Combined paragastric autonomic neural blockade and laparoscopic assisted transversus abdominis plane block
- What this could lead to
- If effective, this combined nerve block approach could offer a new way to manage deep, visceral pain after bariatric surgery, reducing the need for opioids and improving recovery.
- What could go wrong
- This is a single-center trial, and results may not apply broadly. The procedure carries risks like any nerve block, including possible side effects or incomplete pain relief.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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127 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age: 20-50 years, both sexes. * ASA physical status class I to III. * BMI 35- 50 kg/m² Exclusion Criteria: * Severe cardiac disorder * chronic renal failure * liver cirrhosis * allergy to bupivacaine * patients with history of chronic opioid consumption * HBA1C \> 7%
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alexandria University
Alexandria, Egypt
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