New pill tested to fight breast cancer in the brain

NCT ID NCT01494662

Summary

This study tested how well a daily pill called neratinib works for people with a specific type of breast cancer (HER2-positive) that has spread to the brain. The goal was to see if the drug could shrink or stabilize the brain tumors. Researchers also wanted to understand how much of the drug reaches the brain and how previous treatments affected patients' thinking skills.

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Contacts and locations

Locations

  • Arnold Palmer Cancer Center-Greensburg

    Greensburg, Pennsylvania, 15601, United States

  • Baylor College of Medicine Lester and Sue Smith Breast Center

    Houston, Texas, 77030, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hosptial

    Boston, Massachusetts, 02215, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • MedStar Georgetown Univeristy Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21231, United States

  • UPMC Cancer Centers - Magee-Womens Hospital of UPMC

    Pittsburgh, Pennsylvania, 15213, United States

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • UPMC Ortenzio Cancer Center

    Mechanicsburg, Pennsylvania, 17050, United States

  • UPMC Passavant Cranberry

    Cranberry Township, Pennsylvania, 16066, United States

  • UPMC Pinnacle Harrisburg

    Harrisburg, Pennsylvania, 17101, United States

  • University of California, San Francisco Medical Center

    San Francisco, California, 94115, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of North Carolina at Chapel Hill - Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.