Breast cancer drug combo shows promise but study halted early

NCT ID NCT03101748

First seen Feb 17, 2026 · Last updated Jun 14, 2026 · Updated 18 times

Summary

This study tested a mix of targeted drugs (neratinib, pertuzumab, trastuzumab) and chemotherapy (paclitaxel) in people with advanced or inflammatory breast cancer. The goal was to find the best dose and see if the combination could shrink tumors before more chemo. The study was stopped early, but results helped understand side effects and tumor response in 34 participants.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

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