New drug combo aims to wipe out breast cancer before surgery
NCT ID NCT04230109
First seen Nov 01, 2025 · Last updated May 30, 2026 · Updated 23 times
Summary
This study tests a drug called sacituzumab govitecan, given before surgery, in people with localized triple-negative breast cancer. Some participants may also receive pembrolizumab. The goal is to see if the drug can eliminate all signs of cancer in the breast and lymph nodes by the time of surgery. About 260 adults with untreated, hormone receptor-negative and HER2-negative breast cancer are being enrolled.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02115, United States
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital - North Shore Cancer Center
RECRUITINGDanvers, Massachusetts, 01923, United States
Contact Phone: •••-•••-••••
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Massachusetts General Hospital at Newton-Wellesley Hospital
RECRUITINGNewton, Massachusetts, 02462, United States
Contact Phone: •••-•••-••••
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Conditions
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