Could a common antibiotic boost Chemo's power against breast cancer?

NCT ID NCT06452394

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with early-stage ER+/HER2- breast cancer. It tests whether adding doxycycline, a safe and inexpensive antibiotic, to standard chemotherapy can better target cancer stem cells—cells that may cause the cancer to come back. About 50 participants will receive doxycycline alongside their usual chemo before surgery. The goal is to see if this combination improves the chance of eliminating all cancer cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm estrogen-receptor positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Hospitalier Universitaire Vaudois (CHUV)

    RECRUITING

    Lausanne, CH-1011, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Clinique de Genolier

    RECRUITING

    Genolier, Canton of Vaud, 1272, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Graubünden

    RECRUITING

    Chur, Kanton Graubünden, 7000, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital St.Gallen

    RECRUITING

    Sankt Gallen, Canton of St. Gallen, 9007, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Winterthur

    RECRUITING

    Winterthur, Canton of Zurich, 8401, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Réseau du sein Lausanne

    RECRUITING

    Lausanne, 1004, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tumor Zentrum Aarau

    RECRUITING

    Aarau, 5000, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tumor- und Brustzentrum Ostschweiz

    RECRUITING

    Sankt Gallen, 9016, Switzerland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••