New drug duo aims to wipe out lung cancer before surgery

NCT ID NCT07281209

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tests whether giving two drugs (SHR-A1811 and adebelimumab) before surgery can shrink or eliminate tumors in people with early-stage lung cancer that has a specific genetic change (HER2 alteration). About 40 adults with resectable non-small cell lung cancer will receive the combination, then have surgery to remove any remaining cancer. The main goal is to see how many patients have no cancer left at the time of surgery.

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