Immune-boosting combo may shrink colorectal tumors before surgery

NCT ID NCT06154538

First seen Jan 06, 2026 · Last updated May 08, 2026 · Updated 22 times

Summary

This study tests whether adding immune checkpoint inhibitors to standard chemotherapy before surgery can better shrink or eliminate tumors in people with locally advanced colorectal cancer. About 170 adults aged 18 to 75 with stage II/III colorectal cancer will be randomly assigned to receive either the combination or chemotherapy alone. The main goal is to see if the combination leads to a higher rate of complete tumor disappearance at the time of surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital/ National Cancer Center, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100038, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qilu Hospital of Shandong University

    RECRUITING

    Jinan, Shandong, 250000, China

    Contact

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact

    Contact

Conditions

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